Research Interests

Dr Ned Abraham

(Position Details)
Phone Please contact School/Unit
Qualifications MBBS(Hons), MM(Syd) FRACS FRCS(Engl), PhD
 
School/Unit
Rural Clinical School
 
Broad Research Areas
Cancer
Surgery
Evidence Based Medicine
 
Specific Research Keywords
Colorectal cancer
Sphincter Preserving Surgery
Neoadjuvant Therapy
Anal Manometery Biofeedback
Capsule Endoscopy
 
Research Interests

My main areas of interest include Sphincter Preserving Surgery for rectal cancer, Fast Track Surgery for colorectal cancer, ultrasound staging of rectal cancer, anal manometery, Biofeedback & capsule endoscopy. Current research projects include psychological profiling of surgeons and the choice of chemotherapy in neoadjuvant therapy for rectal cancer. I also have links with colorectal researchers at the Surgical Outcomes Research Centre at the University of Sydney. Background Information I am a practicing colorectal cancer surgeon and an officer in the Australian Army Reserve. I graduated with Honours in 1986. My Master’s degree (Sydney 1998) was on the role of smoking in the aetiology of ulcerative colitis. My PhD in Surgery (Sydney 2008) was in one of my main areas of research the role of meta-analysis of non-randomised comparative studies in evidence based surgery. I obtained the Fellowship of the Royal Australasian College of Surgeons in 2002 and was awarded the Fellowship of the Royal College of Surgeons of England through a nomination by its President in 2004. I was the Surgical Superintendent of Royal Prince Alfred Hospital for three years attached to its Colorectal Unit before moving to the UNSW I have worked in the UK & the Middle East and served in Bougainville with the Peace Keeping Force.
 
Society Memberships & Professional Activities
• Supervisor of Advanced and Basic Surgical Training, Coffs Harbour.
• 2007 Runner up New South Wales Department of Health Awards New South Wales Department of Health
• 2004 Fellowship of the Royal College of Surgeons of England (By Invitation) Royal College of Surgeons of England
• 2002 Fellowship of the Royal Australasian College of Surgeons (By Training and Examinations) Royal Australasian College of Surgeons
• 2002 Research Scholarship Colorectal Surgical Society of Australasia
• 1997 The Award of the Division of Surgery for Best Papers presented at Surgical Grand Rounds Royal Prince Alfred Hospital
• The Trevor Taylor Prize, Staff Specialist Committee & The Management Board, Royal Darwin Hospital, December 1995.
• The Patron's Prize, The Medical Board of Royal Prince Alfred Hospital, August 1995.
• The Trevor Taylor Prize, Staff Specialist Committee and The Management Board of the Royal Darwin Hospital, December 1994.
 
Key works/Publications
Lead author in published projects:
1. Abraham N.S. Byrne C.M. Young J.M. Solomon M.J. Meta-analysis of well-designed non-randomised clinical studies of a surgical procedure is as good as randomised controlled trials. (In press) Journal of Clinical Epidemiology) 2009.
2. Abraham N.S. Byrne C.M. Young J.M. Solomon M.J. Meta-analysis of non-randomized comparative studies of the short-term outcomes of laparoscopic resection for colorectal cancer. ANZ Journal of Surgery. 77(7)(pp 508-516), 2007.
3. Abraham N.S. Durairaj R. Young JM. Young CJ. Solomon MJ. How does an historic control study of a surgical procedure compare with the "gold standard"? Diseases of the Colon & Rectum. 49(8):1141-8, 2006.
4. Abraham N. Minimal access colorectal surgery. ANZ Journal of Surgery. 76(5)(pp 285), 2006.
5. Abraham N.S. Hewett P. Young J.M. Solomon M.J. Non-entry of eligible patients into the Australasian Laparoscopic Colon Cancer Study. ANZ Journal of Surgery. 76(9)(pp 825-829), 2006.
6. Abraham NS. Young JM. Solomon MJ. A systematic review of reasons for nonentry of eligible patients into surgical randomized controlled trials. Surgery. 139(4)(pp 469-83), 2006.
7. Abraham N. Lemech L. Sandroussi C. Sullivan D. May J. A prospective study of subclinical myocardial damage in endovascular versus open repair of infrarenal abdominal aortic aneurysms. Journal of Vascular Surgery. 41(3)(pp 377-80; discussion 380-1, 2005.
8. Abraham N.S. Young J.M. Solomon M.J. Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer. British Journal of Surgery. 91(9)(pp 1111-1124), 2004.
9. Abraham N. Eyers A. Pathma-Nathan N. Acute diverticular phlegmon in colonic neovagina. ANZ Journal of Surgery. 74(9)(pp 809-810), 2004.
10. Abraham N. Selby W. Lazarus R. Solomon M. Is smoking an indirect risk factor for the development of ulcerative colitis? An age- and sex-matched case-control study. Journal of Gastroenterology & Hepatology. 18(2)(pp 139-46), 2003.
11. Abraham N. Doudle M. Carson P. Open versus closed surgical treatment of abscesses: a controlled clinical trial. ANZ Journal of Surgery. 67(4)(pp 173-6), 1997.

Co-author in published projects:
12. Ho-Shon K. Waugh R. Abraham N. Solomon M. Angiographic Intervention in the Diagnosis and Treatment of Acute Unstable Lower GI Haemorrhage - A Retrospective Study. Australasian Radiology. 47(2):A7-9, June 2003.
13. Sandroussi C. Lemech L.D. Grunewald B. Abraham N. Gallagher P.J. Late complication following coil embolization of a biliary leak. ANZ Journal of Surgery. 75(7)(pp 614-615), 2005.
14. Selby WS. Griffin S. Abraham N. Solomon MJ. Appendectomy protects against the development of ulcerative colitis but does not affect its course. American Journal of Gastroenterology. 97(11)(pp 2834-8), 2002.

Conference papers converted to published work:
15. The Short Term Outcomes of laparoscopic colectomy for colorectal cancer; a meta-analysis. Ned Abraham, Michael Solomon & Jane Young. ANZ Journal of Surgery, June 2004
16. Does Smoking really protect against the development of ulcerative colitis? An age and sex matched case-control study. Ned Abraham, Warwick Selby, Ross Lazarus & Michael Solomon. ANZ Journal of Surgery, June 1998.
17. Evidence based surgery, where from and where to. Ned Abraham. ANZ Journal of Surgery, June 1998.
18. Open vs. closed surgical treatment of abscesses, A controlled clinical trial. Ned Abraham, Mark Doudle & Phil Carson. ANZ Journal of Surgery, June 1995

Sole author in published work:
19. Ned Abraham. Thesis for the Degree of Doctor of Philosophy (PhD) in Surgery, Faculty of Medicine of The University of Sydney: “A methodological assessment of non-randomised comparative studies as an alternative to the difficult-to-conduct randomised control trials of surgical procedures using the example of laparoscopic colorectal surgery” 2008.
20. Abraham N.S. Will the dilemma of evidence-based surgery ever be resolved? ANZ Journal of Surgery. 76(9)(pp 855-860), 2006.
21. Ned Abraham. Treatise for the Degree of Master of Medicine in Clinical Epidemiology, Faculty of Medicine of University of Sydney. A New Look at the relationship between smoking and the aetiology of ulcerative colitis, a case-control study 1998.
22. Abraham N. The patterns and outcomes of severe thermal injuries in the Australian Top End. [Journal article] The Bulletin of the Australia and New Zealand Burn Association, 17(pp 5-8), 1995.
23. Abraham N. Extreme case of polypharmacy in the elderly. New Ethicals. 32(3)(pp 39-40), 1995.
24. Abraham N. The Dangers of Polypharmacy in the Elderly. [Journal article] Current Therapeutics 36(1)(pp 112-3), 1995.
25. Abraham N. Polypharmacy in the elderly. Australian Family Physician. 23(5)(pp 979-981), 1994.
26. Ned Abraham. The Critically Injured Patient ®: A protocol for the management of severely injured patients in the A&E Department of the Mersey Division of the North West Regional Hospital, Tasmania, 1993 and a review of critically injured patients seen at the Emergency Department of that hospital in the Twenty-four month period between July 1991 and June 1993.

Current submissions:
1. Abraham NS. Cumulative weighted ratio and cumulative weighted difference; a suggested method to collate different forms of continuous data summaries in meta-analysis of comparative studies (ANZ Journal of statistics).

Presentations:
1. Fast Track Colorectal Surgery: A Protocol for a District Hospital. Coffs Harbour Health Campus, June 2006.
2. Wound Management for the General Practitioner. Coffs Harbour Division of General Practice, June 2005.
3. Haemorrhoidectomy: selection of the procedure, indications, pre-operative care and complications. The Training Board in Colon and Rectal Surgery, Second Annual Fellows Education Meeting, Melbourne, August 2004.
4. The Short Term Outcomes of laparoscopic colectomy for colorectal cancer; a meta-analysis. The Royal Australasian College of Surgeons’ Annual Scientific Congress, Melbourne, May 2004
5. The evidence for and against laparoscopic colectomy for colorectal cancer. The Return to Darwin Surgical Meeting, August 2003
6. The Role of angiography and embolisation in the diagnosis and management of massive lower gastrointestinal bleeding. The Annual Meeting of the Colorectal Surgical Society of Australasia, Sydney, October 2001.
7. Does Smoking really protect against the development of ulcerative colitis? An age and sex matched case-control study. The Royal Australasian College of Surgeons’ Annual Scientific Congress, Sydney, May 1998.
8. Quitting Smoking is a risk factor for the aetiology of ulcerative colitis. The Colorectal Journal Club, the Colorectal Surgical Society of Australasia, February 1998.
9. Evidence based surgery, where from and where to. The Royal Australasian College of Surgeons’ Annual Scientific Congress, Sydney, May 1998.
10. An Old Enemy, the epidemiology, clinical manifestations and treatment of tetanus. The University of Sydney's Teaching Hospitals Surgical Division Meeting at Royal Prince Alfred Hospital, February 97.
11. Stable claudication, angioplasty and Stenting, A Browse through the literature. The University of Sydney's Teaching Hospitals Surgical Division Meeting at Royal Prince Alfred Hospital, June 97.
12. The Relationship between smoking and the aetiology of ulcerative colitis. The Registrars Papers Day at the Annual Meeting of New South Wales Branch of the Royal Australasian College of Surgeons, Sydney, September 1997.
13. What would constitute a Potentially Avoidable Death in Trauma? Ned Abraham The University of Sydney's Teaching Hospitals Surgical Division Meeting at Royal Prince Alfred Hospital, June 1997.
14. Evidence based surgery. The University of Sydney's Teaching Hospitals Surgical Division Meeting at Royal Prince Alfred Hospital, The Award of the Division of Surgery for Best Papers presented at Surgical Grand Rounds at RPAH during the year of 1997.
15. A Sad Disease, An experience with the management of a severe case of Fournier’s Gangrene in an Australian Aboriginal male. The University of Sydney's Teaching Hospitals Surgical Division Meeting at Royal Prince Alfred Hospital, October 1997
16. The “new” treatment for acute abscesses. The Registrars Papers Day at the Annual Meeting of the NSW Branch of the Royal Australasian College of Surgeons, Wollongong, September 1996.
17. Open vs. closed surgical treatment of abscesses; A controlled clinical trial. The Royal Australasian College of Surgeons' Annual Scientific Congress, Perth, May 1995
18. The Surgical treatment of abscesses. The Trevor Taylor Presentations, The Staff Specialist Committee & The Management Board, Royal Darwin Hospital, December 1995.
19. The provisional results of a randomised controlled trial of the “new” surgical treatment for abscesses. The University of Sydney's Teaching Hospitals Surgical Division Meeting at Royal Prince Alfred Hospital, June 1995.
20. Surgical treatment of superficial abscesses. Royal Australasian College of Surgeons and The Royal Australasian College of Physicians' Northern Territory Branches' Third Annual Scientific Meeting, Darwin, November 1995.
21. The Ellis Technique for the treatment of surgical abscess. The Annual Meeting of the Medical Board and the Medical Officers Association of the Royal Prince Alfred Hospital, October 1995.
22. Review of burn Cases Admitted to the Royal Darwin Hospital in the twenty four month period between January 1992 and December 1993. The ANZ Burn Association International Annual Conference, Darwin, September 1994.
23. Patterns of severe burn injuries in the Australian Northern Territory. The Trevor Taylor Presentations, The Staff Specialist Committee and The Management Board of the Royal Darwin Hospital, December 1994.

Current projects:
24. The Psychological Profile of Surgeons compared with other professionals.
25. Exploring Bayesian meta-analysis to synthesise surgical research evidence: case study in colorectal surgery.
 


Profile last updated: 2/09/2009

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